Most People Face High Genetic Risk For Around Three Common Diseases, Study Finds
What Happened
A University of Exeter-led study analysing whole-genome data from nearly one million people found that the average person falls within the top 10% of genetic risk for around three of 28 common conditions, including diabetes, cardiovascular disease and schizophrenia. About one in five people ranked in the top 1% for at least one polygenic risk score.
Key Takeaways
High genetic risk does not mean someone will develop a disease. The researchers stress that genetic variation is normal and that other factors are crucial in determining whether disease actually develops.